When they’re full, additional nicotine just won’t do much for you besides make you feel sick. Nicotine stimulates receptors in the brain that release neurotransmitters like dopamine-but the receptors don’t have unlimited capacity. If you use nicotine regularly, you develop a tolerance for some of the effects, as is the case with most drugs, and especially those that have habit-forming properties. And because it has vasoconstricting properties, it tightens the blood vessels and temporarily raises the heart rate and blood pressure, which can cause dizziness, a headrush-or a wave of calmness. When nicotine enters the bloodstream, it travels to the brain and binds with nicotinic cholinergic receptors that reward the user by releasing dopamine and other neurotransmitters that have pleasurable effects. That’s what most nicotine users are seeking. But nicotine’s ability to center the regular user, to relax and refocus, is a standard feature of moderate nicotine use. The buzz comes from using a large dose quickly or being new to the drug. The focus and alertness isn’t necessarily associated with the “buzz” people talk about. Nicotine in small quantities tends to act like a stimulant, while larger doses can have a sedative effect. Notice that that some of those feelings contradict the others. These are the most common statements about how a nicotine buzz feels: Like the drug in coffee and tea, nicotine is a mild stimulant that slightly alters your mental state. Nicotine is the second-most popular stimulant drug in the world, after caffeine. If you don’t want to lose the nic buzz, you have to go without nicotine for extended periods, and not many nicotine users have the discipline to pull that off. The racy feeling experienced by some new nicotine users fades away with continued use. Most adults who vape or smoke regularly aren’t seeking a nicotine or JUUL buzz at all. Most experienced nicotine users simply aren’t chasing the same experience that “novelty users” are. The answers from experienced users are blunt: About 3 days ago I noticed that I’m not getting a nicotine buzz anymore.” I bought a pack of mint pods and they were working great. “So I got a JUUL around 2 weeks ago and I loved it, it gave me a great nic buzz and worked amazing. Are you wondering why you no longer get a JUUL buzz? You’re not alone! Even for those vapers not using a JUUL, online vape forums are peppered with questions by new nicotine users about their e-cigarette buzz disappearing. More precautions and general information are available about nicotine gum.
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